1.
Indian J Exp Biol
;
2000 Jun; 38(6): 610-2
Article
in English
| IMSEAR
| ID: sea-61307
ABSTRACT
A mathematical model has been proposed to study the effect of [TAME] esterase on blood clotting time. Using this model, clotting time was found to decrease by 30% with increasing plasma [TAME] esterase activity in a group of smokers. It is hypothesized that [TAME] esterase through its effect on Hageman factor could affect clotting time. However mechanism of clotting by [TAME] esterase remains to be elucidated. It is concluded that [TAME] esterase is involved in the cascade of reactions leading to blood coagulation and increased [TAME] esterase activity could be an additional risk factor for possible cerebro-vascular accidents in smokers.
Subject(s)
Adult , Aged , Aged, 80 and over , Biomarkers , Blood Coagulation Tests , Cardiovascular Diseases/epidemiology , Comorbidity , Enzyme Activation , Factor XII/metabolism , Humans , Male , Middle Aged , Peptide Hydrolases/blood , Risk Factors , Smoking/adverse effects , Thrombophilia/enzymology
2.
Southeast Asian J Trop Med Public Health
;
1979 Sep; 10(3): 321-4
Article
in English
| IMSEAR
| ID: sea-34284